The SuperAging Research Initiative: Identifying protective factors to promote healthspan

The SuperAging Research Initiative is an international multisite consortium focused on identifying factors promoting superior memory performance beyond the 8th decade. The designation of SuperAger is reserved for individuals age 80+ who have episodic memory capacity that would be considered at least average for those in their 50s and 60s. The original study of SuperAgers emerged more than a decade ago and helped establish the phenotype and is now enrolling across multiple sites in the U.S. and Canada. The SuperAging Research Initiative is focused on increasing minority representation, expanding deep phenotyping, and identifying protective factors important for healthspan. Dr. Rogalski will provide an overview of the SuperAging Research Initiative including, rationale, known features, current progress, and new directions. The study of SuperAgers has unique potential to address questions of fundamental importance to the neurobiology of brain aging, resilience, resistance, and avoidance of cognitive decline associated with typical aging and with Alzheimer’s disease.

Emily Rogalski